Cytogenetics

Faculty
Sainan Wei, PhD, FACMGG
Director of Cytogenetics

CYTOGENETICS LABORATORY

The UK Clinical Cytogenetic Laboratory is certified through the Clinical Laboratory Improvement Act (CLIA), the College of American Pathologists (CAP), and is approved by the Childhood Oncology Group (COG). We provide chromosome analysis on a variety of specimens, including amniotic fluid, chorionic villus samples, tissue biopsies, products of conception, peripheral blood, bone marrow, lymph nodes and solid tumors. Cytogenetic studies are performed for prenatal diagnosis, to investigate infertility, to aid in identifying the cause of spontaneous abortions, to aid in determining the etiology of congenital anomalies, mental retardation, and learning disabilities, and to identify acquired chromosome abnormalities associated with neoplasia.

Constitutional Tests:
• Chromosome Analysis     (Medical Genetics.pdf)
• Chromosome Analysis, Blood      (Medical Genetics.pdf)
• Chromosome Analysis, Amniotic Fluid     (Prenatal.pdf)
• Chromosome Analysis, Chorionic Villus Sample    (Prenatal.pdf)
• Chromosome Analysis, Products of Conception/ Tissue Biopsy   (Medical Genetics.pdf)
• Tissue culture and grow cells for shipment for additional testing     (Medical Genetics.pdf)
• FISH analysis, blood    (Medical Genetics.pdf)  
• CMA (Chromosome microarray , blood (please see Genomics)

Oncology tests:
• Chromosome Analysis, Unstimulated Blood, for Hematologic Disorders    (Oncology.pdf)
• Chromosome Analysis, Bone Marrow, for Hematologic Disorders    (Oncology.pdf)
• Chromosome Analysis, Tumor/Pleural Effusion/ Ascites fluid, for Neoplastic Disorders     (Oncology.pdf)
• FISH analysis, hematology, bone marrow or blood    (Oncology.pdf)
          o Pediatric/Adult AML panel
          o MDS panel
          o MPD panel
          o Pediatric/Adult ALL panels
          o CLL panel
          o MM panels
          o Lymphoma panels
          o Array of individual FISH tests
• FISH Analysis, paraffin Sections (FFPE)   (Oncology.pdf)
          o ERBB2 (HER2) Gene Amplification Status
          o Deletion 1p36/19q13 for glial neoplasia o Lymphoma panel
          o MDM2
          o EWSR1
          o SYT-SS18
          o ROS 1
          o ALK

Cytogenetics Laboratory
University of Kentucky Medical Center
HL423
800 Rose Street
Lexington, Kentucky 40536
Phone: 859-257-3736
Fax: 859-257-6838

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