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Janna Neltner, M.D.
jmhack0's picture
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jmhack0@email.uky.edu
(859) 323-1798
MS 155
Position(s): 
Associate Professor
Director - Pathology Residency Program
Director - Neuropathology Fellowship Program
Affiliation(s): 
Pathology & Laboratory Medicine
Sanders-Brown Center on Aging/Alzheimer’s Disease Research Center
Interests / Specialties: 
Anatomical and Clinical Pathology and Neuropathology
Bio / Education: 

B.S. in Chemistry - University of Kentucky (2001)
MD - University of Kentucky (2006)
AP/CP Residency - University of Kentucky (2010)
Neuropathology Fellowship - University of Kentucky (2012)

Research Description: 

- Pathologic examination of neurodegenerative diseases, including Alzheimer's disease, synucleinopathies, and hippocampal sclerosis (of aging).
- The use of digital image analysis for quantification of findings in neurodegenerative and tumor processes.

Selected Publications: 

Representative Publications & Other Scholarly Work:

Nelson PT, Trojanowski JQ, Abner EL, Al-Janabi OM, Jicha GA, Schmitt FA, Smith CD, Fardo DW, Wang WX, Kryscio RJ, Neltner JH, Kukull WA, Cykowski MD, Van Eldik LJ, Ighodaro ET."New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).  J Neuropathol Exp Neurol. 2016 Jun;75(6):482-98. doi: 10.1093/jnen/nlw033. Epub 2016 May 21. Review.

Bachstetter AD, Ighodaro ET, Hassoun Y, Aldeiri D, Neltner JH, Patel E, Abner EL, Nelson PT. “Rod-shaped microglia morphology is associated with aging in 2 human autopsy series.” Neurobiol Aging. 2017 Apr;52:98-105. doi: 10.1016/j.neurobiolaging.2016.12.028. Epub 2017 Jan 5.

Berger JR, Miller CS, Danaher RJ, Doyle K, Simon KJ, Norton E, Gorelik L, Cahir-McFarland E, Singhal D, Hack N, Owens JR, Nelson PT, Neltner JH. “Distribution and Quantity of Sites of John Cunningham Virus Persistence in Immunologically Healthy Patients: Correlation With John Cunningham Virus Antibody and Urine John Cunningham Virus DNA.  JAMA Neurol. 2017 Feb 27. doi: 10.1001/jamaneurol.2016.5537. [Epub ahead of print]

Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobágyi T, Ironside JW, King A, Kofler J, Kövari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson PT, Ritchie D, Rodriguez RD, Rohan Z, Rozemuller A, Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao M, Rudolf Thal D, Weis S, Wharton SB, White CL 3rd, Woulfe JM, Yamada M, Trojanowski JQ. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). J Neuropathol Exp Neurol. 2017 Jul 1;76(7):605-619. doi: 10.1093/jnen/nlx041.

Tulloch J, Leong L, Chen S, Keene CD, Millard SP, Shutes-David A, Lopez OL, Kofler J, Kaye JA, Woltjer R, Nelson PT, Neltner JH, Jicha GA, Galasko D, Masliah E, Leverenz JB, Yu CE, Tsuang D. APOE DNA methylation is altered in Lewy body dementia. Alzheimers Dement. 2018 Mar 12. pii: S1552-5260(18)30047-5. doi:10.1016/j.jalz.2018.02.005. [Epub ahead of print]

Abner EL, Neltner JH, Jicha GA, Patel E, Anderson SL, Wilcock DM, Van Eldik LJ, Nelson PT. Diffuse Amyloid-β Plaques, Neurofibrillary Tangles, and the Impact of APOE in Elderly Persons' Brains Lacking Neuritic Amyloid Plaques. J Alzheimers Dis. 2018;64(4):1307-1324. doi: 10.3233/JAD-180514.

Garcia CR, Slone SA, Dolecek TA, Huang B, Neltner JH, Villano JL. Primary central nervous system tumor treatment and survival in the United States, 2004-2015. J Neurooncol. 2019 Jun 28. doi: 10.1007/s11060-019-03218-8. [Epub ahead of print]

Sponsored Research Projects, Grants, & Contract Activities:

Co-Investigator for funded research project entitled: Alzheimer’s Disease Core Center. (V. Eldik, PI)

Pathology: (859) 323-5425
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